12 Best Cotton Underwear for Women 2025, Gynecologist Approved

• Why we love them: Come in a variety of absorbencies; breathable for periods, menopause, or everyday leakage; easy to clean
• Worth noting: Pricey

“If your body can’t deal with tampons, menstrual cups, or pads, then Knix’s period underwear is worth trying,” says Glamour commerce producer Leilani McQuay, who has endometriosis, in her review. “I could twist, stretch, and run without feeling like I was wearing a diaper. The high-waist design and breathable fabric were everything I didn’t know I needed—no digging in, no awkward adjusting mid-run, just pure comfort and protection that let me focus on my flow (the yoga kind, not the other kind).” Available in a range of shades, absorbency levels for different points in your cycle, and silhouettes—briefs, bikinis, thongs, even shapewear—the brand’s period underwear is made of moisture-wicking cotton fabric that’s a godsend for managing your flow, navigating menopause, or dealing with everyday leaks.

• Material: 96% cotton, 4%
• Cut: Bikini
• Sizes: XS (hips 33″–35″) to 4X (54″–56″)
• Colors: Black, beige, navy, rose, grey
• Value: $25 each
• Care instructions: Machine-wash