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HRT No Longer Has A Black Box Warning — Here’s What That Means

Until now, all estrogen-containing therapies (creams, patches, pills, and more) carried a “black box” warning, the FDA’s most severe caution label. The warning, introduced after the 2002 Women’s Health Initiative (WHI) study, suggested that hormone therapy could increase the risk of breast cancer, heart attacks, strokes, and dementia, which was deeply flawed.
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